Endocrine Abstracts

Aim and objective: The aims of this study were to determine the incidence of breast cancer molecular subgroups, to investigate the relationship between autoimmune thyroid disease and prognostic and predictive factors in patients who were diagnosed with breast cancer.Materials and methods: One hundred one patients who were followed up with the diagnosis of breast cancer at our Endocrinology and Medical Oncology Departments were included. Patients are divi...

Background and aim: Pheochromocytoma, is a catecholamine-producing tumor, may rarely secrete other hormones such as adrenocorticotropic hormone (ACTH). We aimed to report a rare case of ectopic cushing syndrome due to malignant pheochromocytoma.Case report: A 42-year-old man admitted to outpatient clinic with headache, irritability, vomiting, nausea, and palpitation. He had paroxysmal hypertension and urinary fractionated metanephrines were measured appr...

Introduction and aims: It is known that obesity is associated with retinal microvascular changes. Optical coherence tomography (OCT), a new imaging technique, is used to visualize the choroid. In addition, OCT can also give more beneficial information about systemic and eye diseases. We aim to investigate whether or not obesity may impact on choroid and macula thickness.Material and methods: Forty-four subjects who were apply for obesity in our Endocrino...

Introduction and aim: There are few side effects of cabergoline which is used for medical treatment of prolactinoma. For this reason, cabergoline is considered as first-line therapy of prolactinoma. However, chronic administration of high dose cabergoline in patients with prolactinoma may be associated with valvular heart disease. The aim of this study is to evaluate left ventricular systolic and diastolic functions by conventional and tissue Doppler echocardiography in patien...

Introduction and aim: The metabolic changes of lipid profiles in prolactinoma treated with cabergoline are not completely clarified. The aim of this preliminary study is to evaluate changes of lipid profile in both of patients with functional hyperprolactinemia and prolactinoma before and after cabergoline treatment.Materials and methods: Twelve patients with prolactinoma who were treated with cabergoline (mean age 33.8±7.6 years and body mass index...

Introduction and aim: Mean platelet volume (MPV) is a new important indicator of platelet activity in atherosclerosis. Elevated MPV is associated with the presence of more metabolically active platelets. The aim of our study is to evaluate whether change of MPV value is associated with cabergoline treatment in patients with prolactinoma.Materials and methods: Thirty patients with prolactinoma (mean age 33.4±8.5 years and body mass index (BMI): 28.1&...

Background and aim: Lymphocytic hypophysitis is heterogeneous inflammatory processes of the pituitary gland and may cause isolated hormone deficiency, but rarely occurs as panhypopituitarism. We aim to present a rare case of ulcerative colitis coexisting with lymphocytic hypophysitis.Case report: A 42-years old woman with ulcerative colitis was applied for our department of internal medicine with hypoglycemia. Her capillary blood glucose levels were foun...

Background and aim: Acromegaly is a rare endocrine disease and is associated with an increased prevalence of colorectal cancer and pre-malignant tubular adenomas, and also may be associated with other organ malignancies such as breast and thyroid. We report a rare case of acromegaly concomitant with adenocarcinoma arising from pancreas.Case report: A 52-year-old man who was diagnosed with acromegaly two years ago referred our outpatient clinic. After dia...

Aim: Mean platelet volume (MPV), which is a determinant of platelet function, is an independent risk factor for atherosclerosis. The aim of this study is to evaluate MPV values in gestational diabetes mellitus (GDM).Material and methods: Forty-nine women with gestational diabetes mellitus (mean age 28.2±4.7 years) and 40 healthy pregnant women (mean 26.2±4.6 years age) who came to our Out-Patient Clinic of Endocrinology were included in the stu...

Introduction: Scleredema is a rare skin disease, clinically presents as diffuse, painless induration, and thickening of skin. It primarily affects the upper part of body and usually occurs in association with diabetes mellitus, infections or monoclonal gammopathy. We discussed a case of scleredema in patient with history of diabetes mellitus.Case report: A 54-year-old woman with history of long-standing, poorly-controlled diabetes mellitus, hypertension,...